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Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes
BACKGROUND: Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by mutations affecting UBE3A gene expression. Previous studies in mice revealed distinct critical periods during neurodevelopment in which reactivation of Ube3a gene expression can prevent the onset of behavioral defic...
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| Publicado no: | Mol Autism |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6532248/ https://ncbi.nlm.nih.gov/pubmed/31143434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-019-0277-1 |
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