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Allostery in Coagulation Factor VIIa Revealed by Ensemble Refinement of Crystallographic Structures
A critical step in injury-induced initiation of blood coagulation is the formation of the complex between the trypsin-like protease coagulation factor VIIa (FVIIa) and its cofactor tissue factor (TF), which converts FVIIa from an intrinsically poor enzyme to an active protease capable of activating...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6531671/ https://ncbi.nlm.nih.gov/pubmed/31003762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.024 |
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