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Beating tissue factor at its own game: Design and properties of a soluble tissue factor–independent coagulation factor VIIa
Two decades of research have uncovered the mechanism by which the complex of tissue factor (TF) and the plasma serine protease factor VIIa (FVIIa) mediates the initiation of blood coagulation. Membrane-anchored TF directly interacts with substrates and induces allosteric effects in the protease doma...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6956519/ https://ncbi.nlm.nih.gov/pubmed/31801825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009183 |
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