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Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity

Background: Bupivacaine (Bup) is the most commonly used local anesthetic. However, Bup induces cytotoxicity, especially in older patients. Recent reports have indicated that andrographolide (Andro) exhibits protective effects on human neurons. Nevertheless, whether Andro can inhibit Bup-induced cyto...

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Bibliografski detalji
Izdano u:Drug Des Devel Ther
Glavni autori: Zhang, Huiyuan, Wang, Weiwei, Du, Qian
Format: Artigo
Jezik:Inglês
Izdano: Dove 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529178/
https://ncbi.nlm.nih.gov/pubmed/31190744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S201122
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