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Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity

Background: Bupivacaine (Bup) is the most commonly used local anesthetic. However, Bup induces cytotoxicity, especially in older patients. Recent reports have indicated that andrographolide (Andro) exhibits protective effects on human neurons. Nevertheless, whether Andro can inhibit Bup-induced cyto...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Huiyuan, Wang, Weiwei, Du, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529178/
https://ncbi.nlm.nih.gov/pubmed/31190744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S201122
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