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The Paradox of Akt-mTOR Interactions

The serine threonine protein kinase, Akt, is at the central hub of signaling pathways that regulates cell growth, differentiation, and survival. The reciprocal relation that exists between the two activating phosphorylation sites of Akt, T308 and S473, and the two mTOR complexes, C1 and C2, forms th...

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Détails bibliographiques
Auteurs principaux: Vadlakonda, Lakshmipathi, Dash, Abhinandita, Pasupuleti, Mukesh, Anil Kumar, Kotha, Reddanna, Pallu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687210/
https://ncbi.nlm.nih.gov/pubmed/23802099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00165
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