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The Paradox of Akt-mTOR Interactions

The serine threonine protein kinase, Akt, is at the central hub of signaling pathways that regulates cell growth, differentiation, and survival. The reciprocal relation that exists between the two activating phosphorylation sites of Akt, T308 and S473, and the two mTOR complexes, C1 and C2, forms th...

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Hlavní autoři: Vadlakonda, Lakshmipathi, Dash, Abhinandita, Pasupuleti, Mukesh, Anil Kumar, Kotha, Reddanna, Pallu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687210/
https://ncbi.nlm.nih.gov/pubmed/23802099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00165
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