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The Paradox of Akt-mTOR Interactions
The serine threonine protein kinase, Akt, is at the central hub of signaling pathways that regulates cell growth, differentiation, and survival. The reciprocal relation that exists between the two activating phosphorylation sites of Akt, T308 and S473, and the two mTOR complexes, C1 and C2, forms th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3687210/ https://ncbi.nlm.nih.gov/pubmed/23802099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00165 |
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