MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

The MYC oncoprotein binds to promoter-proximal regions of virtually all transcribed genes and enhances RNA polymerase II (Pol II) function, but its precise mode of action is poorly understood. Using mass spectrometry of both MYC and Pol II complexes, we show here that MYC controls the assembly of Po...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Baluapuri, Apoorva, Hofstetter, Julia, Dudvarski Stankovic, Nevenka, Endres, Theresa, Bhandare, Pranjali, Vos, Seychelle Monique, Adhikari, Bikash, Schwarz, Jessica Denise, Narain, Ashwin, Vogt, Markus, Wang, Shuang-Yan, Düster, Robert, Jung, Lisa Anna, Vanselow, Jens Thorsten, Wiegering, Armin, Geyer, Matthias, Maric, Hans Michael, Gallant, Peter, Walz, Susanne, Schlosser, Andreas, Cramer, Patrick, Eilers, Martin, Wolf, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527870/
https://ncbi.nlm.nih.gov/pubmed/30928206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.031
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados