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PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters

The Myc oncogene is a transcription factor with a powerful grip on cellular growth and proliferation. The physical interaction of Myc with the E-box DNA motif has been extensively characterized, but it is less clear whether this sequence-specific interaction is sufficient for Myc’s binding to its tr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gerlach, Jennifer M., Furrer, Michael, Gallant, Maria, Birkel, Dirk, Baluapuri, Apoorva, Wolf, Elmar, Gallant, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676885/
https://ncbi.nlm.nih.gov/pubmed/29078288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705816114
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