Načítá se...

Different promoter affinities account for specificity in MYC-dependent gene regulation

Enhanced expression of the MYC transcription factor is observed in the majority of tumors. Two seemingly conflicting models have been proposed for its function: one proposes that MYC enhances expression of all genes, while the other model suggests gene-specific regulation. Here, we have explored the...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Lorenzin, Francesca, Benary, Uwe, Baluapuri, Apoorva, Walz, Susanne, Jung, Lisa Anna, von Eyss, Björn, Kisker, Caroline, Wolf, Jana, Eilers, Martin, Wolf, Elmar
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963202/
https://ncbi.nlm.nih.gov/pubmed/27460974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15161
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!