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Different promoter affinities account for specificity in MYC-dependent gene regulation
Enhanced expression of the MYC transcription factor is observed in the majority of tumors. Two seemingly conflicting models have been proposed for its function: one proposes that MYC enhances expression of all genes, while the other model suggests gene-specific regulation. Here, we have explored the...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963202/ https://ncbi.nlm.nih.gov/pubmed/27460974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15161 |
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