Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody

Depletion of T regulatory cells (Tregs) in the tumor microenvironment is a promising cancer immunotherapy strategy. Current approaches for depleting Tregs are limited by lack of specificity and concurrent depletion of anti-tumor effector T cells. The transcription factor forkhead box p3 (Foxp3) play...

詳細記述

保存先:
書誌詳細
出版年:Oncoimmunology
主要な著者: Dao, Tao, Mun, Sung Soo, Scott, Andrew C., Jarvis, Casey A., Korontsvit, Tatyana, Yang, Zhiyuan, Liu, Lianxing, Klatt, Martin G., Guerreiro, Manuel, Selvakumar, Annamalai, Brea, Elliott J., Oh, Claire, Liu, Cheng, Scheinberg, David A.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2019
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527296/
https://ncbi.nlm.nih.gov/pubmed/31143508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1570778
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