T cell receptor mimic antibodies for cancer therapy

The major hurdle to the creation of cancer-specific monoclonal antibodies (mAb) exhibiting limited cross-reactivity with healthy human cells is the paucity of known tumor-specific or mutated protein epitopes expressed on the cancer cell surface. Mutated and overexpressed oncoproteins are typically c...

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Publicat a:Oncoimmunology
Autors principals: Dubrovsky, Leonid, Dao, Tao, Gejman, Ron S, Brea, Elliott J, Chang, Aaron Y, Oh, Claire Y, Casey, Emily, Pankov, Dmitry, Scheinberg, David A
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760335/
https://ncbi.nlm.nih.gov/pubmed/26942058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1049803
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