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Opportunities and challenges for TCR mimic antibodies in cancer therapy
INTRODUCTION: Monoclonal antibodies (mAbs) are potent cancer therapeutic agents, but exclusively recognize cell-surface targets whereas most cancer-associated proteins are found intracellularly. Hence, potential cancer therapy targets such as overexpressed self-proteins, activated oncogenes, mutated...
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| Publicado no: | Expert Opin Biol Ther |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936943/ https://ncbi.nlm.nih.gov/pubmed/27094818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2016.1176138 |
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