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Human cytomegalovirus protein UL42 antagonizes cGAS/MITA-mediated innate antiviral response
Cyclic GMP-AMP synthase (cGAS) senses viral DNA in the cytosol and then catalyzes synthesis of the second messenger cGAMP, which activates the ER-localized adaptor protein Mediator of IRF3 Activator (MITA) to initiate innate antiviral response. Human cytomegalovirus (HCMV) proteins can antagonize ho...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527189/ https://ncbi.nlm.nih.gov/pubmed/31107917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007691 |
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