cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection

Several innate sensing pathways contribute to the control of early cytomegalovirus (CMV) infection, leading to a multiphasic type I interferon (IFN-I) response that limits viral replication and promotes host defenses. Toll-like receptor (TLR)-dependent pathways induce IFN-I production in CMV-infecte...

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Gepubliceerd in:J Virol
Hoofdauteurs: Lio, Chan-Wang J., McDonald, Bryan, Takahashi, Mariko, Dhanwani, Rekha, Sharma, Nikita, Huang, Jenny, Pham, Elise, Benedict, Chris A., Sharma, Sonia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Cellular Response to Infection
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988162/
https://ncbi.nlm.nih.gov/pubmed/27334590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01040-16
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