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Human Cytomegalovirus DNA Polymerase Subunit UL44 Antagonizes Antiviral Immune Responses by Suppressing IRF3- and NF-κB-Mediated Transcription

Innate immunity is the first line of host defense against viral invasion. The induction of type I interferons (IFNs) and inflammatory cytokines is essential to host antiviral immune responses, which are also key targets of viral immune evasion. Human cytomegalovirus (HCMV) can establish long-term la...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fu, Yu-Zhi, Su, Shan, Zou, Hong-Mei, Guo, Yi, Wang, Su-Yun, Li, Shu, Luo, Min-Hua, Wang, Yan-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532097/
https://ncbi.nlm.nih.gov/pubmed/30867312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00181-19
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