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Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response
Cyclic GMP-AMP synthase (cGAS) senses double-stranded DNA and synthesizes the second messenger cyclic GMP-AMP (cGAMP), which binds to mediator of IRF3 activation (MITA) and initiates MITA-mediated signaling, leading to induction of type I interferons (IFNs) and other antiviral effectors. Human cytom...
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| Publicado en: | J Virol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307088/ https://ncbi.nlm.nih.gov/pubmed/32238587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00022-20 |
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