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Delicate regulation of the cGAS–MITA-mediated innate immune response

Although it has long been demonstrated that cytosolic DNA is a potent immune stimulant, it is only in recent years that the molecular mechanisms of DNA-stimulated innate immune responses have emerged. Studies have established critical roles for the DNA sensor cyclic GMP–AMP synthase (cGAS) and the a...

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Detalles Bibliográficos
Publicado en:Cell Mol Immunol
Main Authors: Luo, Wei-Wei, Shu, Hong-Bing
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123429/
https://ncbi.nlm.nih.gov/pubmed/29456253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.51
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