Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils

α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central nervous system (CNS) inoculation studies using either in vitro polymerized αS fibrils or in vivo derived lysates containing αS aggregates...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Dhillon, Jess-Karan S., Trejo-Lopez, Jorge A., Riffe, Cara, Levites, Yona, Sacino, Amanda N., Borchelt, David R., Yachnis, Anthony Y., Giasson, Benoit I.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526622/
https://ncbi.nlm.nih.gov/pubmed/31109378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0733-3
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