TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma

Hepatoblastoma (HB) is the most common type of pediatric liver cancer. Activation of yes-associated protein (YAP) has been implicated in HB molecular pathogenesis. The transcriptional co-activator Yap regulates downstream gene expression through interaction with the TEA domain (TEAD) proteins. Nonet...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Pathol
Hauptverfasser: Zhang, Jie, Liu, Pin, Tao, Junyan, Wang, Pan, Zhang, Yi, Song, Xinhua, Che, Li, Sumazin, Pavel, Ribback, Silvia, Kiss, Andras, Schaff, Zsuzsa, Cigliano, Antonio, Dombrowski, Frank, Cossu, Carla, Pascale, Rosa M., Calvisi, Diego F., Monga, Satdarshan P., Chen, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2019
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526503/
https://ncbi.nlm.nih.gov/pubmed/30794805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.01.016
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge