Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are recruited to the cortex by Gαi-sub...

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Publicado en:Nat Commun
Main Authors: Pirovano, Laura, Culurgioni, Simone, Carminati, Manuel, Alfieri, Andrea, Monzani, Silvia, Cecatiello, Valentina, Gaddoni, Chiara, Rizzelli, Francesca, Foadi, James, Pasqualato, Sebastiano, Mapelli, Marina
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525239/
https://ncbi.nlm.nih.gov/pubmed/31101817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09999-w
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