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On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN

Alignment of the mitotic spindle to the cellular polarity axis is a prerequisite for asymmetric cell divisions. The protein network coordinating the spindle position with cortical polarity includes the molecular machinery pulling on astral microtubules, which is assembled on conserved NuMA:LGN:Gαi c...

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Hlavní autoři: Mapelli, Marina, Gonzalez, Cayetano
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438535/
https://ncbi.nlm.nih.gov/pubmed/22977735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.120102
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