SLK-dependent activation of ERMs controls LGN–NuMA localization and spindle orientation

Mitotic spindle orientation relies on a complex dialog between the spindle microtubules and the cell cortex, in which F-actin has been recently implicated. Here, we report that the membrane–actin linkers ezrin/radixin/moesin (ERMs) are strongly and directly activated by the Ste20-like kinase at mito...

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Detalhes bibliográficos
Main Authors: Machicoane, Mickael, de Frutos, Cristina A., Fink, Jenny, Rocancourt, Murielle, Lombardi, Yannis, Garel, Sonia, Piel, Matthieu, Echard, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068135/
https://ncbi.nlm.nih.gov/pubmed/24958772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201401049
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