Structures of the LGN/mInsc and LGN/NuMA complexes suggest distinct functions of the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways in asymmetric cell division

Asymmetric cell division requires the establishment of cortical cell polarity and the orientation of the mitotic spindle along the axis of cell polarity. Evidence from invertebrates demonstrates that the Par3/Par6/aPKC and NuMA/LGN/Gαi complexes, which are thought to be physically linked by the adap...

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Detalhes bibliográficos
Main Authors: Zhu, Jinwei, Wen, Wenyu, Zheng, Zhen, Shang, Yuan, Wei, Zhiyi, Xiao, Zhuoni, Pan, Zhu, Du, Quansheng, Wang, Wenning, Zhang, Mingjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158460/
https://ncbi.nlm.nih.gov/pubmed/21816348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.07.011
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