Ric-8A and Giα Recruit LGN, NuMA, and Dynein to the Cell Cortex To Help Orient the Mitotic Spindle

In model organisms, resistance to inhibitors of cholinesterase 8 (Ric-8), a G protein α (Gα) subunit guanine nucleotide exchange factor (GEF), functions to orient mitotic spindles during asymmetric cell divisions; however, whether Ric-8A has any role in mammalian cell division is unknown. We show he...

Full description

Saved in:
Bibliographic Details
Main Authors: Woodard, Geoffrey E., Huang, Ning-Na, Cho, Hyeseon, Miki, Toru, Tall, Gregory G., Kehrl, John H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897540/
https://ncbi.nlm.nih.gov/pubmed/20479129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00394-10
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items