Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

The large nuclear mitotic apparatus (NuMA) protein is an essential player in mitotic spindle assembly and maintenance. We report here the identification of Astrin, a spindle- and kinetochore-associated protein, as a novel interactor of NuMA. We show that the C-terminal tail of NuMA can directly bind...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Chu, Xiaogang, Chen, Xuanyu, Wan, Qingwen, Zheng, Zhen, Du, Quansheng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025691/
https://ncbi.nlm.nih.gov/pubmed/27462074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.724831
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