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Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

The large nuclear mitotic apparatus (NuMA) protein is an essential player in mitotic spindle assembly and maintenance. We report here the identification of Astrin, a spindle- and kinetochore-associated protein, as a novel interactor of NuMA. We show that the C-terminal tail of NuMA can directly bind...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chu, Xiaogang, Chen, Xuanyu, Wan, Qingwen, Zheng, Zhen, Du, Quansheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025691/
https://ncbi.nlm.nih.gov/pubmed/27462074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.724831
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