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Cell cycle–regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation

Accurate and efficient separation of sister chromatids during anaphase is critical for faithful cell division. It has been proposed that cortical dynein–generated pulling forces on astral microtubules contribute to anaphase spindle elongation and chromosome separation. In mammalian cells, however, d...

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Autors principals: Zheng, Zhen, Wan, Qingwen, Meixiong, Gerry, Du, Quansheng
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937087/
https://ncbi.nlm.nih.gov/pubmed/24371089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-08-0474
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