The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics

Eukaryotic cells typically form a single, round nucleus after mitosis, and failures to do so can compromise genomic integrity. How mammalian cells form such a nucleus remains incompletely understood. NuMA is a spindle protein whose disruption results in nuclear fragmentation. What role NuMA plays in...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Serra-Marques, Andrea, Houtekamer, Ronja, Hintzen, Dorine, Canty, John T., Yildiz, Ahmet, Dumont, Sophie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Rockefeller University Press 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555356/
https://ncbi.nlm.nih.gov/pubmed/33044554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004202
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