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Regulation of mitotic spindle assembly factor NuMA by Importin-β

Ran–guanosine triphosphatase orchestrates mitotic spindle assembly by modulation of the interaction between Importin-α/-β and spindle assembly factors (SAFs). The inhibition of SAFs performed by importins needs to be done without much sequestration from abundant nuclear localization signal (NLS) –co...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Chang, Chih-Chia, Huang, Tzu-Lun, Shimamoto, Yuta, Tsai, Su-Yi, Hsia, Kuo-Chiang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674899/
https://ncbi.nlm.nih.gov/pubmed/28939615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705168
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