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NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
The positioning and the elongation of the mitotic spindle must be carefully regulated. In human cells, the evolutionary conserved proteins LGN/Gα(i1-3) anchor the coiled-coil protein NuMA and dynein to the cell cortex during metaphase, thus ensuring proper spindle positioning. The mechanisms governi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195763/ https://ncbi.nlm.nih.gov/pubmed/24996901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488147 |
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