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NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function

Spindle positioning and spindle elongation are critical for proper cell division. In human cells, an evolutionary conserved ternary complex (NuMA/LGN/Gαi) anchors dynein at the cortex during metaphase, thus ensuring correct spindle positioning. Whether this complex contributes to anaphase spindle el...

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Bibliografische gegevens
Hoofdauteurs: Kotak, Sachin, Busso, Coralie, Gönczy, Pierre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: European Molecular Biology Organization 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770949/
https://ncbi.nlm.nih.gov/pubmed/23921553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.172
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