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NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function
Spindle positioning and spindle elongation are critical for proper cell division. In human cells, an evolutionary conserved ternary complex (NuMA/LGN/Gαi) anchors dynein at the cortex during metaphase, thus ensuring correct spindle positioning. Whether this complex contributes to anaphase spindle el...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770949/ https://ncbi.nlm.nih.gov/pubmed/23921553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.172 |
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