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NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function

Spindle positioning and spindle elongation are critical for proper cell division. In human cells, an evolutionary conserved ternary complex (NuMA/LGN/Gαi) anchors dynein at the cortex during metaphase, thus ensuring correct spindle positioning. Whether this complex contributes to anaphase spindle el...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kotak, Sachin, Busso, Coralie, Gönczy, Pierre
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: European Molecular Biology Organization 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770949/
https://ncbi.nlm.nih.gov/pubmed/23921553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.172
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