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NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function

Spindle positioning and spindle elongation are critical for proper cell division. In human cells, an evolutionary conserved ternary complex (NuMA/LGN/Gαi) anchors dynein at the cortex during metaphase, thus ensuring correct spindle positioning. Whether this complex contributes to anaphase spindle el...

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書誌詳細
主要な著者: Kotak, Sachin, Busso, Coralie, Gönczy, Pierre
フォーマット: Artigo
言語:Inglês
出版事項: European Molecular Biology Organization 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770949/
https://ncbi.nlm.nih.gov/pubmed/23921553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.172
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