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NuMA interaction with chromatin is vital for proper chromosome decondensation at the mitotic exit

NuMA is an abundant long coiled-coil protein that plays a prominent role in spindle organization during mitosis. In interphase, NuMA is localized to the nucleus and hypothesized to control gene expression and chromatin organization. However, because of the prominent mitotic phenotype upon NuMA loss,...

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Pubblicato in:Mol Biol Cell
Autori principali: Rajeevan, Ashwathi, Keshri, Riya, Kapoor, Sukriti, Kotak, Sachin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851854/
https://ncbi.nlm.nih.gov/pubmed/32845810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-06-0415
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