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Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions
Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are recruited to the cortex by Gαi-sub...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525239/ https://ncbi.nlm.nih.gov/pubmed/31101817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09999-w |
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