Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are recruited to the cortex by Gαi-sub...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Pirovano, Laura, Culurgioni, Simone, Carminati, Manuel, Alfieri, Andrea, Monzani, Silvia, Cecatiello, Valentina, Gaddoni, Chiara, Rizzelli, Francesca, Foadi, James, Pasqualato, Sebastiano, Mapelli, Marina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525239/
https://ncbi.nlm.nih.gov/pubmed/31101817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09999-w
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