De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency

CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery is impaired in cancer cells. Here, we conducted a comprehensive analysis of CGI methy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Reports
Prif Awduron: Yagi, Masaki, Kabata, Mio, Ukai, Tomoyo, Ohta, Sho, Tanaka, Akito, Shimada, Yui, Sugimoto, Michihiko, Araki, Kimi, Okita, Keisuke, Woltjen, Knut, Hochedlinger, Konrad, Yamamoto, Takuya, Yamada, Yasuhiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524733/
https://ncbi.nlm.nih.gov/pubmed/31056481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.008
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