De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency
Summary: CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery is impaired in cancer cells. Here, we conducted a comprehensive analysis of...
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| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2019-05-01
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| Seri Bilgileri: | Stem Cell Reports |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2213671119301304 |
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