De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency
Summary: CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery is impaired in cancer cells. Here, we conducted a comprehensive analysis of...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019-05-01
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| Serie: | Stem Cell Reports |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2213671119301304 |
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