A Glutathione S-Transferase π-Activated Prodrug Causes Kinase Activation Concurrent with S-Glutathionylation of Proteins

Nitric oxide (NO) is an endogenous, diffusible, transcellular messenger shown to affect regulatory and signaling pathways with impact on cell survival. Exposure to NO can impart direct post-translational modifications on target proteins such as nitration and/or nitrosylation. As an alternative, afte...

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Vydáno v:Mol Pharmacol
Hlavní autoři: Townsend, Danyelle M., Findlay, Victoria J., Fazilev, Farit, Ogle, Molly, Fraser, Jacob, Saavedra, Joseph E., Ji, Xinhua, Keefer, Larry K., Tew, Kenneth D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522256/
https://ncbi.nlm.nih.gov/pubmed/16288082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.105.018523
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