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The Role of Glutathione S-transferase P in signaling pathways and S-glutathionylation in Cancer

Glutathione S-transferase P is abundantly expressed in some mammalian tissues, particularly those associated with malignancies. While the enzyme can catalyze thioether bond formation between some electrophilic chemicals and GSH, novel non-detoxification functions are now ascribed to it. This review...

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Detalhes bibliográficos
Main Authors: Tew, Kenneth D., Manevich, Yefim, Grek, Christina, Xiong, Ying, Uys, Joachim, Townsend, Danyelle M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125017/
https://ncbi.nlm.nih.gov/pubmed/21558000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.04.013
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