Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO

PABA/NO is a diazeniumdiolate selectively activated by glutathione S-transferase P (GSTP) to release nitric oxide (NO) and is a potent inducer of protein S-glutathionylation, a redox-sensitive post-translational modification of cysteine residues. Using a procedure that incrementally increased exposu...

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Hauptverfasser: Hutchens, Steven, Manevich, Yefim, He, Lin, Tew, Kenneth D., Townsend, Danyelle M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912140/
https://ncbi.nlm.nih.gov/pubmed/20232108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9407-5
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