A Glutathione S-Transferase π-Activated Prodrug Causes Kinase Activation Concurrent with S-Glutathionylation of Proteins

Nitric oxide (NO) is an endogenous, diffusible, transcellular messenger shown to affect regulatory and signaling pathways with impact on cell survival. Exposure to NO can impart direct post-translational modifications on target proteins such as nitration and/or nitrosylation. As an alternative, afte...

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Publicado en:Mol Pharmacol
Main Authors: Townsend, Danyelle M., Findlay, Victoria J., Fazilev, Farit, Ogle, Molly, Fraser, Jacob, Saavedra, Joseph E., Ji, Xinhua, Keefer, Larry K., Tew, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522256/
https://ncbi.nlm.nih.gov/pubmed/16288082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.105.018523
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