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Efficacy of a Glutathione S-Transferase π-activated Prodrug in Platinum-resistant Ovarian Cancer Cells
Human ovarian carcinoma cells (C70 and C200) made resistant to cisplatin from A2780 cells demonstrated an ~20-fold resistance to the drug. These same cell lines showed no collateral resistance (as compared with the wild-type) to a novel glutathione S-transferase π-activated prodrug {γ-glutamyl-α-ami...
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| Veröffentlicht in: | Mol Cancer Ther |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522260/ https://ncbi.nlm.nih.gov/pubmed/12481432 |
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