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Dynamin‐like protein 1 cleavage by calpain in Alzheimer’s disease
Abnormal mitochondrial dynamics contributes to mitochondrial dysfunction in Alzheimer's disease (AD), yet the underlying mechanism remains elusive. In the current study, we reported that DLP1, the key mitochondrial fission GTPase, is a substrate of calpain which produced specific N‐terminal DLP...
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| Gepubliceerd in: | Aging Cell |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516178/ https://ncbi.nlm.nih.gov/pubmed/30767411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12912 |
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