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Dynamin‐like protein 1 cleavage by calpain in Alzheimer’s disease

Abnormal mitochondrial dynamics contributes to mitochondrial dysfunction in Alzheimer's disease (AD), yet the underlying mechanism remains elusive. In the current study, we reported that DLP1, the key mitochondrial fission GTPase, is a substrate of calpain which produced specific N‐terminal DLP...

詳細記述

保存先:
書誌詳細
出版年:Aging Cell
主要な著者: Jiang, Sirui, Shao, Changjuan, Tang, Fangqiang, Wang, Wenzhang, Zhu, Xiongwei
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516178/
https://ncbi.nlm.nih.gov/pubmed/30767411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12912
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