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Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage

The dynamin-related protein Opa1 is localized to the mitochondrial intermembrane space, where it facilitates fusion between mitochondria. Apoptosis causes Opa1 release into the cytosol and causes mitochondria to fragment. Loss of mitochondrial membrane potential also causes mitochondrial fragmentati...

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Bibliografske podrobnosti
Main Authors: Griparic, Lorena, Kanazawa, Takayuki, van der Bliek, Alexander M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064541/
https://ncbi.nlm.nih.gov/pubmed/17709430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704112
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