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Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage

The dynamin-related protein Opa1 is localized to the mitochondrial intermembrane space, where it facilitates fusion between mitochondria. Apoptosis causes Opa1 release into the cytosol and causes mitochondria to fragment. Loss of mitochondrial membrane potential also causes mitochondrial fragmentati...

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Détails bibliographiques
Auteurs principaux: Griparic, Lorena, Kanazawa, Takayuki, van der Bliek, Alexander M.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064541/
https://ncbi.nlm.nih.gov/pubmed/17709430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704112
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