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Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
The dynamin-related protein Opa1 is localized to the mitochondrial intermembrane space, where it facilitates fusion between mitochondria. Apoptosis causes Opa1 release into the cytosol and causes mitochondria to fragment. Loss of mitochondrial membrane potential also causes mitochondrial fragmentati...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064541/ https://ncbi.nlm.nih.gov/pubmed/17709430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704112 |
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