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Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer’s Disease Patients

Mitochondrial function relies heavily on its morphology and distribution, alterations of which have been increasingly implicated in neurodegenerative diseases, such as Alzheimer’s disease (AD). In this study, we found abnormal mitochondrial distribution characterized by elongated mitochondria that a...

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Détails bibliographiques
Auteurs principaux: Wang, Xinglong, Su, Bo, Fujioka, Hisashi, Zhu, Xiongwei
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475784/
https://ncbi.nlm.nih.gov/pubmed/18599615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071208
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