Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer’s Disease Patients

Mitochondrial function relies heavily on its morphology and distribution, alterations of which have been increasingly implicated in neurodegenerative diseases, such as Alzheimer’s disease (AD). In this study, we found abnormal mitochondrial distribution characterized by elongated mitochondria that a...

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Main Authors: Wang, Xinglong, Su, Bo, Fujioka, Hisashi, Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475784/
https://ncbi.nlm.nih.gov/pubmed/18599615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071208
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