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Dynamin‐like protein 1 cleavage by calpain in Alzheimer’s disease

Abnormal mitochondrial dynamics contributes to mitochondrial dysfunction in Alzheimer's disease (AD), yet the underlying mechanism remains elusive. In the current study, we reported that DLP1, the key mitochondrial fission GTPase, is a substrate of calpain which produced specific N‐terminal DLP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging Cell
Päätekijät: Jiang, Sirui, Shao, Changjuan, Tang, Fangqiang, Wang, Wenzhang, Zhu, Xiongwei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516178/
https://ncbi.nlm.nih.gov/pubmed/30767411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12912
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